Harvard University: Creating 3-D tissue and its potential for regeneration

Bioprinting technique may provide potential for tissue repair and regenerative medicine


Researchers are one step closer to embedding vascular networks into thick human tissues, which could result in tissue repair and regeneration — and ultimately even replacement of whole organs.

 A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University and the Harvard John A. Paulson School for Engineering and Applied Sciences (SEAS) has invented a method for 3-D bioprinting thick vascularized tissue constructs. The vasculature network enables fluids, nutrients, and cell growth factors to be perfused uniformly throughout the tissue.

The advance was reported Monday in the journal Proceedings of the National Academy of Sciences.


“This latest work extends the capabilities of our multi-material bioprinting platform to thick human tissues, bringing us one step closer to creating architectures for tissue repair and regeneration,” says the study’s senior author, Jennifer A. Lewis, who is a Wyss core faculty member and the Hansjörg Wyss Professor of Biologically Inspired Engineering at SEAS.
Read more - . http://news.harvard.edu/gazette

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